پژوهش در طب ورزشی و فناوری

مطالعۀ تغییرات آدیپونکتین، لپتین و نیم‌رخ لیپیدی پلاسمای خون مردان غیرفعال بر اثر 24 جلسه بازی فوتسال

نویسندگان

رضا امینی
حمید رجبی
محمد رضا امیرسیف الدینی
کوروس دیوسالار
https://doi.org/10.18869/acadpub.jsmt.14.12.11
چکیده
هدف این پژوهش بررسی تعیین تغییرات آدیپونکتین، لپتین و نیم­رخ لیپیدی پلاسمای خون مردان غیرفعال به دنبال 24 جلسه بازی فوتسال است. در این مطالعه 20 مرد سالم 30-20 ساله و غیرفعال، به­طور تصادفی به دو گروه تجربی (سن: 2/58±23/5، وزن: 14/48±69/36 کیلوگرم، شاخص تودۀ بدنی: 4/41±22/82 کیلوگرم بر مترمربع) و گروه کنترل (سن: 2±24/6 سال، وزن: 12/71±68/22 کیلوگرم، شاخص تودۀ بدنی: 3/58±21/99 کیلوگرم بر مترمربع) تقسیم شدند. گروه تجربی در هر جلسه برنامۀ تمرینی فوتسال شامل 20 دقیقه گرم­کردن، دو زمان 30 دقیقه­ای بازی فوتسال و درنهایت 10 دقیقه سردکردن را به­مدت هشت­هفته و هر هفته سه جلسه اجرا انجام داد و گروه کنترل فعالیت عادی خود را سپری کرد. قبل­از برنامۀ تمرینی و 48 ساعت پس­از پایان آخرین جلسۀ بازی، نمونۀ خون به­میزان 5 میلی­لیتر، جهت اندازه­گیری میزان آدیپونکتین، لپتین و نیم­رخ لیپیدی پلاسمای خون از آزمودنی­ها جمع­آوری و با استفاده از آزمون t مستقل تجزیه و تحلیل شد. نتایج حاصل نشان داد که 24 جلسه بازی فوتسال باعث افزایش معنی­دار لیپوپروتئین پرچگال (0/03=p) و کاهش معنی­دار لپتین (0/04=p)، لیپوپروتئین کم­چگال (0/03=p)، لیپوپروتئین(a) (0/04=p)،، تری­گلیسیرید (0/03=p) و کلسترول (0/03=p) می­شود، با وجود این، تفاوت­ها دربارۀ آدیپونکتین (0/04=p) معنی­دار نبود (0/05≥p). به نظر می­رسد فعالیت بدنی ناشی از بازی فوتسال موجب تغییراتی در میزان برخی هورمون‌های ترشح شده از بافت چربی سفید و دیگر ارگان­های مرتبط با ترشح این هورمون‌ها می­شود، ولی با وجود نتایج متناقض به­دست­آمده در تحقیقات گذشته، بررسی­های بیشتر در این باره ضروری به نظر می­رسد.

کلیدواژه‌ها

آدیپونکتین
لپتین
نیم‌رخ لیپیدی
فوتسال

عنوان مقاله English

Study of changes in adiponectin, leptin, and plasma lipid profile of Inactive men the result 24 session, playing futsal

نویسندگان English

Reza Amini
Hamid Rajabi
Mohamad Reza Amir Seifadini
Koros Divsalar
چکیده English

The aim of the study, study of Changes in adiponectin, leptin, and plasma lipid profile of Inactive men the result 24 session, playing futsal. In this study, 20 healthy men 20 to 30 years old, the experimental group (age: 23/5±2/58, weight: 69/36±14/48, body composition: 22/82±4/41) of controls (age: 24/6±2, weight: 68/22±12/71, body composition: 21/99±3/58) inactive randomly divided into control and experimental groups. Experimental groups in each session, indoor futsal training program for eight weeks and will run three sessions per week, while the control group had normal activity. Before the training program, and 48 h after the last session of play, 5 ml blood samples for measurement of adiponectin, leptin, and plasma lipid profile, blood was collected from the participants. After 48 hours of the last training session before the test was re-sampled in the same conditions. T-test results showed that exercise increased adiponectin and high-density lipoprotein and decreased leptin, low density lipoprotein, lipoprotein (a), triglycerides and cholesterol are, however, differences in adiponectin was not significant (P≤0.05). Overall, this study can be taken that these exercises in a short period of eight weeks futsal, adiponectin does not cause significant changes but the significant changes in leptin, high-density lipoprotein, low density lipoprotein, lipoprotein (a), triglycerides and cholesterol in the blood plasma.

کلیدواژه‌ها English

Adiponectin
Leptin
Lipid Profile
Futsal
6. Rontu, R., Metso, S., Jaakkola, O., Nikkila, M., Jokela, H., Lehtimaki, T. (2005). Antibody titer against malondialdehyde-modified LDL compares with HDL cholesterol concentration in identifying angiographically verified coronary artery disease. Comparison of tests by ROC analysis. Clin Chem Lab. 43(4): 357-60.
7. Kraemer, Robert. R., and Castracane. V, Daniel. (2007). Exercise and Humoral Mediators of Peripheral Energy Balance: Ghrelin and Adiponectin. Experimental Biology and Medicine 232:184-194.
8. Dela, F., Mikines, K.J., Sonne, B., Galbo, H. (1994). Effect of training on interaction between insulin and exercise in human muscle. Journal of Applied Physiology. Vol. 76 no. 6, 2386-2393. PMID:7928862.
10. Eriksson, Maria., Owe, Johnson., Kurt, Boman., Göran, Hallmans., Gideon, Hellsten., Torbjörn. K, Nilsson., and Stefan, Söderberg. (2008). Improved fibrinolytic activity during exercise may be an effect of the adipocyte-derived hormones leptin and adiponectin.Thrombosis Research. 122(5): 701-708.
11. Terry. E, Jones., J.L, Basilio., P.M, Brophy., M.R, McCammon., and R.C, Hickner. (2009). Long-term exercise training in overweight adolescents improves plasma peptide YY and resistin. Obesity doi:10.1038/oby.
12. Davis, P.G., Rankinen, T., Leon, A.S., Rao, D.C., Skinner, J.S., Wilmore, J.H., Bouchard, C. (2006). Effect of Endurance Exercise Training on Serum Adiponectin Concentration. Medicine & Science in Sports & Exercise. 38(5):S45.
13. Bernstein, E.L., Koutkia, P., Ljungquist, K., Breu, J., Canavan, B., Grinspoon, S. (2004). Acute regulation of adiponectin by free acids. Metabolism. 53(6):790-3.
14. Baecke, J.A., Burema, J., Frijters, J.E. (1982). A short questionnaire for the measurement of habitual physical activity in epidemiological studies. The American Journal of Clinical Nutrition. 36(5):936-42.
15. Foster, C., Jackson, A.S., Pollock, M.L., Taylor, M.M., Hare, J., Sennett, S.M., Rod, J.L., Sarwar, M., Schmidt, D.H. (1984). Generalized equations for predicting functional capacity from treadmill performance. American Heart Journal. 107(6):1229-34.
17. Rampinini, E., Impellizzeri, F., Castagna, C., Abt, G., Chamari, K., Sassi, A., Marcora, S.M. (2007). Factors influencing physiological responses to small-sided soccer games. Journal of Sport Sciences. 25(6):659–66.
18. Rebelo. A.N., Ascenção, A., Magalhães, J., Krustrup, P. (2007). Activity profile, heart rate and blood lactate of Futsal referees during competitive games. With world congress on science and football. BOOK OF ABSTRACTS. Journal of Sports Science and Medicine. Suppl. 10, 94.
19. Friedewald, W.T., Levy, R.I., Fredrickson, D.S. (1972). Estimation of the concentration of low- density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry. 18(6): 499-502.
21. Hulver, M.W., Zheng, D., Tanner, C.J., Houmard, J.A., Kraus, W.E., Slentz, C.A., Sinha, M.K., Pories, W.J., MacDonald, K.G., Dohm, G.L. (2002). Adiponectin is not altered with exercise training despite enhanced insulin
action. American Journal of Physiology. Endocrinology and Metabolism. 283: E861-E865
23. Bobbert, T., Wegewitz, U., Brechtel, L., Freudenberg, M., Mai, K., Möhlig, M., Diederich, S., Ristow, M., Rochlitz, H., Pfeiffer, A.F., Spranger, J. (2007). Adiponectin oligomers in human serum during acute and chronic exercise. relation to lipid metabolism and insulin sensitivity. International journal of sports medicine International journal of sports medicine. International Journal of Sports Medicine. 28(1): 1-8.
24. Wang, J.S., Chow, S.E. (2004). Effect of exercise training and detraning on oxidized low-density lipoprotein-potentiated platelet function in men. Archives of Physical Medicine and Rehabilitation. 85(9):1531-1537.
25. Kim, E.S., Im, J.A., Kim, K.C., Park, J.H., Suh, S.H., Kang, E.S., Kim, S.H., Jekal, Y., Lee, C.W., Yoon, Y.J., Lee, H.C., Jeon, J.Y. (2007). Improved insulin sensitivity and adiponectin level after exercise training in obese Korean youth. Obesity (Silver Spring). 15(12):3023-30.
26. Lowndes, J., Zoeller, R.F., Caplan, J.D., Kyriazis, G.A., Moyna, N.M., Seip, R.L., Thompson, P.D., Angelopoulos, T.J. (2008). Leptin responses to long-term cardiorespiratory exercise training without concomitant weight loss: a prospective study. The Journal of Sports Medicine and Physical Fitness. 48(3):391-7.
27. Coker, R.H., Hays, N.P., Kortebein, .P.M., Sullivan, D.H., Freeling, S.A., Williams, R.H., Yeo, S.E., Evans, W.J. (2006). Plasma Adiponectin is not Altered by Moderate or Heavy Aerobic Exercise Training in Elderly, Overweight Individuals. Medicine & Science in Sports & Exercise. 38(5): p S189. DOI: 10.1249/00005768-200605001-00854.
28. Holme, I., Urdal, P., Anderssen, S., Hjermann. I (1996). Exercise-induced increase in lipoprotein (a). Atheroscleroisis. 122(1): 97-104.
29. Halle, M., Berg, A., von Stein, T., Baumstark, M.W., Konig, D., Keul, J. (1996). Lipoprotein(a) in endurance athletes, power athletes, and sedentary controls. Medicine and Science in Sports and Exercise. 28(8): 962-966.
32. Jurimae, J., Purge, P., Jurimae, T. (2006). Adiponectin and stress hormone responses to maximal sculling after volume- extended training season to elite rowers. Metabolism. Metabolism 55(1): 13-19.
33. Huang, H., Iida. K,T., Sone, H., Ajisaka, R. (2007). The regulation of adiponectin receptors expression by acute exercise in mice. Search Results Experimental and Clinical Endocrinology & Diabetes.115.(7): 417-22.
34. O'Leary, V.B., Jorett, A.E., Marchetti, C.M., Gonzalez, F., Phillips, S.A., Ciaraldi, T.P., Kirwan, J.P. (2007). Enhanced adiponectin multimer ratio and skeletal muscle adiponectin receptor expression following exercise training and diet in older insulin- esistant adults. American Journal of Physiology-Endocrinology and Metabolism. 293(1): E421-7.
35. Marcell, T.J., MCAuley, K.A., Traustadottir, T., Reaven, P.D. (2005). Exercise training is not associated with improved levels of C-reactire protein or adiponectin. Metabolism Clinical and Experimental. 54(4): 533–41.
36. Zhang, Y., Zhang, Y., Mills, P.J., Rehman, J. (2006). Dynamic Exercise Can Acutely Increase Circulating Adiponectin. American Heart Association. Inc. Circulation.114: 881-2.
37. Jurimae, J., Purge, P., Jurimae, T. (2005). Adiponectin is altered after maximal exercise in highly trained male rowers. European Journal of Applied Physiology. 93(4): 502-5.
38. Jamurtas, A.Z., Theocharis, V., Koukoulis, G., Stakias, N., Fatouros, I.G., Kouretas, D., Koutedakis, Y. (2006). The effects of acute exercise on serum adiponectin and resistin levels and their relation to insulin sensitivity in overweight males. European Journal of Applied Physiology. 97: 122-6.
40. Zeng, Q., Fu, L., Takekoshi, K., Kawakami, Y., Isobe, K. (2007). Effects of short-term exercise on adiponectin and adiponectin receptor levels in rats. Journal of Atherosclerosis and Thrombosis. 14(5): 261-5.