پژوهش در طب ورزشی و فناوری

تأثیر شش‌هفته تمرین مقاومتی تناوبی بر سطوح سرمی ائوتاکسین و عامل نروتروفیک مشتق از مغز در مردان جوان با اضافه وزن

نویسندگان

وحید فکری کورعباسلو
پژمان معتمدی
صادق امانی شلمزاری
چکیده
ائوتاکسین آدیپوکین پیش التهابی مترشحه از بافت چربی است که ترشح آن در چاقی افزایش یافته و مانع نوروژنز می­‌شود. BDNF نیز یکی از عوامل رشد عصبی است که در عملکرد شناختی، متابولیسم چربی و قند و همچنین پاتوفیزیولوژی چاقی و سندرم متابولیک در بزرگسالی مؤثر است. هدف از مطالعه حاضر تعیین تاثیر شش‌­هفته تمرین مقاومتی تناوبی بر سطوح سرمی ائوتاکسین و عامل نروتروفیک مشتق از مغز در مردان جوان با اضافه­‌وزن بود. ۲۰دانشجوی غیرفعال و فاقد برنامه ورزشی منظم از دانشگاه خوارزمی انتخاب و به صورت تصادفی به دوگروه تمرین (۱۰نفر) و کنترل (۱۰نفر) تقسیم شدند. گروه تمرین به مدت شش­‌هفته، سه‌­جلسه در هفته و هرجلسه به مدت ۴۵دقیقه در تمرینات حضور داشتند. برنامه تمرینی شامل هفت­‌حرکت با شدت ۳۰-۴۰درصد ۱RM و سرعت ۲v به مدت ۱۰ثانیه و فواصل استراحتی با شدت ۳۰-۴۰درصد ۱RM و سرعت v0/5 به مدت ۲۰ثانیه بود. نمونه­های خونی قبل و پس از شش‌­هفته تمرین، اخذ و مقادیر ائوتاکسین و BDNF سرمی با روش الایزا اندازه‌­گیری شد. برای تجزیه و تحلیل داده­‌ها از آزمون کوواریانس و آزمون تعقیبی بونفرونی برای مقایسه متغیرها و همبستگی پیرسون استفاده شد. نتایج تحلیل کوواریانس و آزمون بونفرونی نشان‌­دادند که شش­‌هفته تمرین مقاومتی تناوبی موجب کاهش معناداری در شاخص‌­های پیکرسنجی مثل توده‌­ی بدنی (۰/۰۰۳=p)، شاخص توده بدن (۰/۰۰۴=p)، دور کمر (۰/۰۱۲=p) و درصد چربی (۰/۰۰۱=p) شد؛ همچنین، این روش موجب افزایش معنی‌­دار در استقامت عضلانی (۰/۰۰۱=p)، و سطوح BDNF سرمی گروه تمرین نسبت به گروه کنترل گردید (۰/۰۲۴=p)؛ همچنین، سطوح ائوتاکسین سرمی در گروه تمرین کاهش معنی‌­داری داشت (۰/۰۲۲=p). نتایج همبستگی هم نشان‌­داد بین ائوتاکسین و BDNF پیش و پس از آزمون به ترتیب رابطۀ معکوس معنی‌­داری وجود دارد (0/511=p=0/013 r=0/586 ، p=0/015 r) . کاهش وزن در اثر شش­‌هفته تمرین مقاومتی تناوبی که همراه با از دست‌­دادن بافت چربی بوده است، موجب کاهش سطوح سرمی ائوتاکسین و افزایش سطوح سرمی BDNF گردیده است.

(0=p=0/013 r

کلیدواژه‌ها

تمرین مقاومتی تناوبی
ائوتاکسین
BDNF
اضافه‌وزن

عنوان مقاله English

The effect of six weeks of interval resistance training on eotaxin and brain-derived neurotrophic factor serum levels in overweight young men

نویسندگان English

Vahid Fekri Kourabbaslou
Pezhman Motamedi
Sadegh Amani Shalamzari
چکیده English

Eotaxin, a pro-inflammatory Adipokine is secreted from adipose tissue, which its secretion increases in the obesity and cause neurodegeneration. BDNF is a neurological factor that interferes with cognitive function, fat and sugar metabolism, as well as the pathophysiology of obesity and metabolic syndrome in adulthood. The aim of this study was to investigate the Effect of Six Weeks of Interval Resistance Training on Eotaxin and Brain-Derived Neurotrophic Factor Serum Levels in Overweight young men. Twenty non-active students without regular exercise program from Kharazmi University were randomly selected and divided into two groups of training (n=10) and control (n=10). The training group performed Interval resistance Training for 6 weeks, 3 sessions per week and each session lasted 45 minutes. The training program included 7 moves with intensity of 30-40% of 1RM and velocity 2v for 10 seconds and rest intervals with intensity 30-40% 1RM and velocity v for 20 seconds. Blood samples were taken before and after 6 weeks of training to evaluate the serum Eotaxin and BDNF levels using the Sandwich ELISA. To analyze the data, the covariance test and Bonferron's post hoc test were used to compare the variables. The results of covariance analysis and Bonferroni test showed that 6 weeks of Interval resistance training caused a significant reduction in the weight (p=0.003), body mass index (p=0.004) Waist circumference (p=0.012) and fat percentage (p=0.001). Also, significant increase was observed in muscular endurance (p=0.001), serum BDNF levels in the training group compared to the control group (p=0.024), and serum Eotaxin levels in the training group decreased significantly (p=0.022). Correlation results showed a significant reverse relationship respectively between pre and post training Eotaxin and BDNF (p=0.015 r=-0.511, p=0.013 r=-0.586). Weight loss through six weeks of Interval Resistance training, which accompanied the loss of adipose tissue; resulted in a reduction in serum levels of Eotaxin and increased serum levels of BDNF.

کلیدواژه‌ها English

Interval Resistance Training
Eotaxin
BDNF
Overweight
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